Table 3.
Clinical outcomes
| Clinical event | No fiducial (n = 46) | Fiducial (n = 50) | uHR/uOR | P | aHR/aOR | P |
|---|---|---|---|---|---|---|
| Local recurrence-free survival | 52.2% | 68.0% | 0.7 (0.4-1.3)∗ | .27 | 0.6 (0.3-1.3) | .59 |
| Overall survival | 67.4% | 58.0% | 1.4 (0.7-2.7)∗ | .34 | 0.8 (0.3-1.9)∗ | .65 |
| LRRFS | 50.0% | 62.0% | 0.8 (0.4-1.5)∗ | .55 | 0.7 (0.3-1.5)∗ | .71 |
| DMFS | 50.0% | 44.0% | 1.4 (0.8-2.5)∗ | .23 | 1.1 (0.5-2.2)∗ | .86 |
| PFS | 34.8% | 34.0% | 0.9 (0.6-1.6)∗ | .86 | 1.0 (0.5-1.9)∗ | .99 |
| Post-SBRT surgery | 50.0% | 36.0% | 0.6 (0.2-1.3)† | .17 | 0.6 (0.3-1.4)† | .26 |
| Positive margins | 17.4% | 29.4% | 2.0 (0.4-8.9)† | .37 | 2.1 (0.4-11.4)† | .40 |
| LVIS | 56.5% | 62.5% | 1.3 (0.3-4.7)† | .71 | 1.2 (0.3-5.0)† | .76 |
Abbreviation: aHR = adjusted hazard ratio; aOR = adjusted odds ratio; DMFS = distant metastasis-free survival; LRRFS = local-regional recurrence-free survival; LVIS = lympho-vascular invasion; PFS = progression-free survival; SBRT = stereotactic body radiation therapy; uHR = unadjusted hazard ratio; uOR = unadjusted odds ratio.
Adjusted hazard ratio and adjusted odds ratio were adjusted for age, gender, Eastern Cooperative Oncology Group performance status, chemotherapy, type of image guided radiation therapy , tumor stage, and tumor site.
∗
Hazard ratio calculated.
†
Odds ratio calculated.