Table 2.
Patient characteristics at initial presentation (n = 10)
| Characteristics | n (%) or mean ± standard deviation |
|---|---|
| Age (y) | 61 ± 10 |
| Sex | |
| Male | 8 (80%) |
| Female | 2 (20%) |
| Weight (kg) | 82.8 ± 24.3 |
| Height (m) | 1.8 ± 0.12 |
| ∗Individual tumor volume (mL) | 965 ± 1242 |
| †Tumor burden (%) | 46 ± 21 |
| <25% | 1 (10%) |
| 25%-50% | 4 (40%) |
| >50% | 5 (50%) |
| ‡Total tumor volume (mL) | 1737 ± 1226 |
| §Extrahepatic metastases | |
| Lung and lymph node | 1 (10%) |
| Prostate | 1 (10%) |
| Rectum | 1 (10%) |
| Prior treatment | |
| Primary HCC resection | 1 (10%) |
| Chemotherapy | 0 (0%) |
| Radiation therapy | 0 (0%) |
| Ablation | 0 (0%) |
| Concurrent treatment | 0 (0%) |
| Therapies after EBRT + SIRT (sorafenib) | 1 (10%) |
| Portal vein thrombosis | 3 (30%) |
| Hepatitis | |
| Type B | 0 (0%) |
| Type C | 6 (60%) |
| Number of tumors per patient | 1.8 ± 0.8 |
| 1 | 4 (40%) |
| 2 | 4 (40%) |
| 3 | 2 (20%) |
| Targeted liver lobe | |
| Right | 3 (30%) |
| Left | 1 (10%) |
| Both | 6 (60%) |
| SIRT treatment delivered before EBRT | 2 (20%) |
| Body surface area (m2) | 1.86 ± 0.32 |
| ‖Lung-shunt (%) | 7.3 ± 4.7 |
| Administered 90Y activity (MBq) | 1934 ± 293 |
| EBRT dose schedule | |
| 7 fractions of 3 Gy | 8 (80%) |
| 6 fractions of 3 Gy | 1 (10%) |
| 5 fractions of 10 Gy | 1 (10%) |
| EBRT photon beam energy (MV) | 11 ± 6 |
| 6 MV | 4 (40%) |
| 10 MV | 3 (30%) |
| 18 MV | 1 (10%) |
| 23 MV | 1 (10%) |
| 6 MV + 23 MV | 1 (10%) |
| EBRT treatment time (d) | 8.6 ± 1.1 |
Abbreviations: EBRT = external beam radiation therapy; HCC = hepatocellular carcinoma; SIRT = selective internal radiation therapy.
∗
All tumors considered independently before any radiation therapy
†
Percent (%) of whole liver occupied by tumor before any radiation therapy
‡
Cumulative volume of tumors from the last computed tomography (CT) before any radiation therapy
§
Three distinct patients
‖
Missing data for 1 patient