Table 3.
Clinical characteristics of the participants classified by the pulmonary fibrosis
| Non-PF | PF | p | ||
|---|---|---|---|---|
| Reversible | Irreversible | |||
| N | 175 | 80 | 34 | |
| Male (%) | 76 (43.4) | 33 (41.2) | 21 (61.8) | 0.106 |
| Age, years | 55.00 [38.00, 67.00] | 59.00 [50.00, 66.00] | 61.50 [55.25, 71.75] | 0.025 |
| Severe (%) | 7 (4.0) | 26 (32.5) | 30 (88.2) | <0.001 |
| KL-6, U/mL | 318.67 [237.61, 413.11] | 417.29 [265.19, 586.93] | 942.51 [703.62, 1132.31] | <0.001 |
| CRP, mg/mL | 0.12 [0.05, 0.97] | 0.26 [0.12, 2.39] | 1.97 [0.15, 3.26] | 0.003 |
| Symptom, N | ||||
| Fever (%) | 112 (64.0) | 53 (66.2) | 22 (64.7) | 0.941 |
| Cough (%) | 95 (54.3) | 47 (58.8) | 26 (76.5) | 0.056 |
| Panting (%) | 37 (21.1) | 30 (37.5) | 23 (67.6) | <0.001 |
| Fatigue (%) | 74 (42.3) | 36 (45.0) | 19 (55.9) | 0.344 |
| Blood cell analysis | ||||
| Leukocyte, 109/L | 4.66 [1.99, 6.63] | 5.44 [4.57, 8.52] | 5.00 [3.00, 7.51] | 0.008 |
| Lymphocyte, 109/L | 1.58 [1.22, 2.00] | 1.46 [1.06, 1.71] | 1.06 [0.87, 1.40] | <0.001 |
| Neutrophil, 109/L | 3.19 [2.45, 4.20] | 3.56 [2.76, 5.24] | 3.79 [3.22, 5.12] | 0.010 |
| Biochemical detection | ||||
| K, mmol/L | 4.22 [3.94, 4.44] | 4.19 [3.88, 4.49] | 4.14 [3.70, 4.49] | 0.660 |
| Na, mmol/L | 140.10 [138.33, 141.98] | 140.70 [137.70, 142.70] | 139.60 [138.40, 141.50] | 0.589 |
| Cl, mmol/L | 104.40 [102.70, 106.40] | 104.45 [102.07, 106.25] | 101.90 [98.70, 104.60] | 0.013 |
| Ca, mmol/L | 2.28 [2.20, 2.38] | 2.23 [2.09, 2.38] | 2.30 [2.20, 2.35] | 0.260 |
PF: Pulmonary fibrosis; CRP: C-reactive protein.