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. 2021 Apr 12;8:647508. doi: 10.3389/fmolb.2021.647508

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Copyright © 2021 Yang, Huang, Fan and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The abundance of ACE2, transmembrane serine protease (TMPRSS2) and tissue tropism of SARS-CoV-2 infection. (A) Violin plots for the levels of ACE2 and TMPRSS2 expression across various cell types among different tissues from healthy donors. (B) The distribution of ACE2 protein in the respiratory and digestive tracts from healthy individuals, by immunohistochemical imaging. (C) Images of gastrointestinal tissues from COVID-19 patients with immunofluorescent staining of SARS-CoV-2 NP. Reproduced with permission (Xiao et al., 2020; Zhang H. et al., 2020). Copyright 2020, the British Medical Journal and American Gastroenterological Association.