Figure 8.

Gut microbiome changes after antioxidant NAC treatment in MRL/lpr mice. Bacterial DNA was isolated from fecal pellets of CON and NAC-treated MRL/lpr mice, and 16s rDNA sequencing was performed to evaluate the microbiome composition in each mice. (A) The variety of organisms in a community termed as alpha diversity. (B) Different mouse strains showed distinct microbiome pattern. (C) Stacked bar plot for composition of common bacterial taxa (>0.1% abundance). (D) Taxa relative abundance at family level. (E) Taxa relative abundance at genus level. Results are mean ± SEM. n = 5 *p < 0.05.