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. 2021 Apr 12;11:598001. doi: 10.3389/fonc.2021.598001

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Copyright © 2021 Nota, Al-Sukaini, Patel, Sabbatino, Nielsen, Deshpande, Yearley, Ferrone, Wang and Schwab

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Representative immunohistochemical staining patterns of primary chondrosarcoma tumors with HLA class I subunit specific monoclonal antibodies. (A) HLA-A positive stain in dedifferentiated chondrosarcoma (100x magnification). (B) HLA-A negative stain in grade 1 chondrosarcoma with positive bone marrow (200x magnification). (C) HLA-B, -C positive stain in dedifferentiated chondrosarcoma (100x magnification). (D) HLA-B, -C positive stain in grade 2 chondrosarcoma (400x magnification). (E) HLA-B, -C negative stain in grade 3 chondrosarcoma (200x magnification). (F); HLA-B, -C positive stain in grade 3 chondrosarcoma (200x magnification). (G) β2m both a positive and negative stain in grade 1 chondrosarcoma (400x magnification). (H) β2m positive stain in grade 2 chondrosarcoma (200x magnification). (I) β2m negative stain in grade 2 chondrosarcoma (200x magnification).