Table 4.

TIL, HLA Class I subunit and HLA Class II antigen expression in metastasis and in primary tumors.

A. Combined dedifferentiated and conventional chondrosarcoma combined
	Primary				Metastasis
	#	Mean (cell #)	SD (%)	Range (%)	#	Mean (cell #)	SD (%)	Range (%)	Observation	P-value
CD4+	61	0.16	1.0	0-7.9	7	0.080	0.11	0-0.25	Lower	0.090
CD8+	62	5.0	11	0-52	6	2.7	4.4	0-11	Lower	0.16
HLA	#	Mean (%)	SD (%)	Range (%)	#	Mean (%)	SD (%)	Range (%)
A Heavy Chain	70	46	31	10-90	6	66	27	20-90	Higher	0.59
B, C Heavy Chain	72	55	31	10-90	7	83	7.6	75-90	Higher	0.17
B2m	70	40	26	10-90	7	62	24	30-90	Higher	0.22
Class II	68	29	27	10-90	7	53	33	10-83	Higher	0.17
B. Conventional chondrosarcoma
Primary					Metastasis
	#	Mean (cell #)	SD (%)	Range (%)	#	Mean (cell #)	SD (%)	Range (%)	Observation	P-value
CD4+	39	0.030	0.059	0-0.20	3	0.10	0.091	0-0.17	Higher	0.17
CD8+	42	0.63	2.5	0-14	3	0	NA	0-0	Lower	NA
HLA	#	Mean (%)	SD (%)	Range (%)	#	Mean (%)	SD (%)	Range (%)
A Heavy Chain	50	31	23	10-83	3	49	30	20-80	Higher	0.29
B, C Heavy Chain	52	42	26	10-85	3	78	5.8	75-85	Higher	0.11
B2m	51	32	23	10-87	3	57	25	30-80	Higher	0.29
Class II	48	14	7.5	10-55	3	19	16	10-38	Higher	0.78
C. Dedifferentiated chondrosarcoma
Primary					Metastasis
	#	Mean (cell #)	SD (%)	Range (%)	#	Mean (cell #)	SD (%)	Range (%)	Observation	P-value
CD4+	22	0.39	1.7	0-7.9	4	0.063	0.13	0-0.25	Lower	0.32
CD8+	20	14	15	0-52	3	5.4	5.1	0.5-11	Lower	0.18
HLA	#	Mean (%)	SD (%)	Range (%)	#	Mean (%)	SD (%)	Range (%)
A Heavy Chain	20	83	10	55-90	3	83	7.6	75-90	Equal	0.65
B, C Heavy Chain	20	90	1.5	85-90	4	86	7.5	75-90	Lower	0.32
B2m	19	59	25	10-90	4	67	26	30-90	Higher	0.65
Class II	20	67	19	33-90	4	78	4.1	75-83	Higher	0.18