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. 2021 Apr 12;12:652383. doi: 10.3389/fimmu.2021.652383

Table 2.

Routine laboratory findings and immunological results of enrolled patients.

  PJP patients non-PJP patients *P-Value AUC
Routine blood examination
 WBC (×109/L) 8.23 (3.99-12.22) 8.15 (5.39-10.91) 0.683
 NEU (×109/L) 7.13 (3.28-10.41) 6.52 (4.07-8.96) 0.613
 LYM (×109/L) 0.53 (0.13-2.12) 0.97 (0.45-2.90) <0.001 0.812
 MON (×109/L) 0.33 (0.06-1.07) 0.45 (0.21-0.70) 0.043 0.632
 EOS (×109/L) 0.00 (0.00-0.13) 0.01 (0.00-0.22) 0.183
 RBC (×1012/L) 3.33 (2.48-5.80) 3.96 (3.22-4.70) 0.001 0.713
 Hb (g/L) 101.2 (76.3-177.4) 116.6 (89.2-144.1) 0.004 0.687
Routine biochemical examination
 TP (g/L) 56.9 (47.0-103.9) 62.8 (54.2-71.3) 0.006 0.679
 ALB (g/L) 28.7 (21.6-50.3) 36.9 (31.5-42.4) <0.001 0.819
 GLB (g/L) 28.3 (20.9-49.2) 26.1 (21.3-30.8) 0.108
 A/G (g/L) 0.99 (0.58-2.22) 1.44 (1.17-1.70) <0.001 0.766
 LDH (U/L) 473 (219-692) 229 (151-369) <0.001 0.823
Lymphocyte subsets
 CD3+ T cells (%) 64.58 (43.17-88.74) 75.32 (64.57-86.08) <0.001 0.736
 CD3+ T cell number (/μl) 261 (89-1187) 863 (398-2209) <0.001 0.911
 CD4+ T cells (%) 30.96 (18.53-49.49) 39.02 (18.12-49.92) 0.013 0.662
 CD4+ T cell number (/μl) 117 (14-582) 397 (225-1817) <0.001 0.902
 CD8+ T cells (%) 30.45 (15.99-46.44) 33.65 (21.31-45.99) 0.184
 CD8+ T cell number (/μl) 118 (23-469) 395 (150-1050) <0.001 0.888
 CD19+ B cells (%) 18.47 (6.55-25.01) 11.92 (4.12-19.72) 0.016 0.656
 CD19+ B cell number (/μl) 64 (0-332) 101 (1-546) 0.016 0.656
 CD56+ NK cells (%) 12.84 (2.82-37.03) 9.10 (2.23-37.79) 0.039 0.634
 CD56+ NK cell number (/μl) 58 (5-296) 98 (23-729) 0.006 0.679
 CD4+ T cell number (/μl)/CD8+ T cell number (/μl) 1.39 (0.39-1.78) 1.13 (0.47-3.39) 0.718  

PJP, Pneumocystis jiroveci pneumonia; AUC, area under the curve; WBC, white blood cells; NEU, Neutrophils; LYM, lymphocytes, MON, monocytes; EOS, Eosinophils; RBC, red blood cells; Hb, hemoglobin; TP, total protein; ALB, albumin; GLB, globulin; A/G, albumin/globulin; LDH, lactate dehydrogenase; *Comparisons were performed between PJP group and non-PJP group using Mann-Whitney U test chi-square test. Data are presented as number (percentage), means ± SD, or medians (2.5th - 97.5th centiles).