Figure 1.

Adult Hippocampal Neurogenesis in Mice

(A) Schematic representation of the mouse hippocampus. The panel on the left illustrates a coronal cut through the dorsal hippocampus of a mouse brain. The panel on the right is a coronal section through the dorsal hippocampus.

(B) Schematic representation of adult hippocampal neurogenesis in the mouse. Quiescent NSCs become activated to generate daughter cells that either return to quiescence for self-renewal of the NSC pool or differentiate into neurons. Neural progenitors that survive beyond the early survival stage mature into granule neurons and integrate into hippocampal circuitry. Markers expressed throughout the phases of neurogenesis are shown.