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. 2021 Apr 12;12:624404. doi: 10.3389/fphar.2021.624404

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Copyright © 2021 Xuan, Xi, Zhang, Tao, Zhang and Cao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Yiqi Jiedu Huayu decoction (YJHD) alleviates podocyte injury. (A) Podocin and nephrin expression were detected by immunohistochemistry. (B, C) Immunohistochemical staining results of podocin and nephrin were analyzed by Image-Pro Plus software. (D) Protein levels of podocin and nephrin in kidneys were detected by western blot. (E, F) Protein concentration analysis. Data are expressed as *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001: compared with the normal control group; #p < 0.05, ##p < 0.01, ###p < 0.001: compared with the diabetic group.