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. 2021 Apr 12;11:656078. doi: 10.3389/fonc.2021.656078

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Copyright © 2021 Mo, He, Zheng, Chen, Tang and Yan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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tRF-17-79MP9PP suppresses breast cancer cell malignant activity. (A) The expression of tRF-17-79MP9PP in normal mammary epithelial cell lines MCF-10A and breast cancer cells. (B) Cell viability of breast cancer cell lines after transfection with tRF-17-79MP9PP mimics or mimics control and detection by CCK-8 assay. (C, D) Colony formation assay and Edu assay of treated cells. (E) Cell cycle analysis in treated cells by flow cytometry. (F) Representative images and bar graphs were depicted to investigate the migration and invasion ability in treated cells. *p < 0.05; ** p < 0.01, statistically significant.