Figure 3.

IPC-Enriched Genes Encode for Variety of Signaling Pathway Factors

(A) Graphical representation of the top-ranked signaling pathways that are prominent in IPCs.

(B, D, F, H, J, L, N, and P) List of the genes identified in IPCs that are involved in the p53, Caspase, Hippo, Notch, FoxO, PI3K-Akt, Axon guidance, and Fanconi anemia signaling pathways, respectively.

(C, E, G, I, K, M, O, and Q) Respective array of micrographs showing in situ hybridization of examples of the identified signaling pathway-linked genes (highlighted red in the adjoining gene list) with distinctive expression in the developing mouse cortical subventricular zone. Magnified cortical region is shown by a red box in (C). Scale bar, 100 μm.