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Impact of vaccine-acquired immunity period on peak hospitalization, when vaccination starts at early (Month 0), rising (Month 3), and peak (Month 4) stages of the epidemic, for I1-S0 (a) and I0-S0 (b) vaccines. As the immunity durability decreases, an early vaccination loses its relative impact. I0 denotes a vaccine that prevents transmission (I1, otherwise), and S0 is a vaccine that can reduce the severity of symptoms in case of inadequate primary response (S1, otherwise).
