Table 2.
The relative expression of the differentially expressed genes in the corresponding key pathways.
| Pathway name | Symbol | Description | Log2 (fold change) | P value |
|---|---|---|---|---|
| Cell Cycle | CDK2 | Cyclin dependent kinase 2 | 1.264 | 0.0085 |
| CDC6 | Cell division cycle 6 | 1.263 | 0.0151 | |
| ORC6 | Origin recognition complex subunit 6 | 1.314 | 0.0360 | |
| ORC1 | Origin recognition complex subunit 1 | 1.587 | 0.0455 | |
| CDC25A | Cell division cycle 25A | 1.887 | 0.0256 | |
| CDC45 | Cell division cycle 45 | 1.427 | 0.0185 | |
| CHEK1 | Checkpoint kinase 1 | 0.875 | 0.0296 | |
| CHEK2 | Checkpoint kinase 2 | 0.810 | 0.0033 | |
| CCNA2 | Cyclin A2 | 1.122 | 0.0026 | |
| CCNB2 | Cyclin B2 | 1.222 | 0.0086 | |
| MCM2 | Minichromosome maintenance complex component 2 | 1.402 | 0.0127 | |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | 0.828 | 0.0001 | |
| MCM7 | Minichromosome maintenance complex component 7 | 1.144 | 0.0255 | |
| CCNE1 | Cyclin E1 | 1.228 | 0.0015 | |
| ESPL1 | Extra spindle pole bodies like 1, separase | 1.612 | 0.0150 | |
| Toll-like receptor signaling pathway | IL12B | Interleukin 12B | 2.791 | 0.0026 |
| TLR4 | Toll like receptor 4 | −1.478 | 0.0401 | |
| TLR3 | Toll like receptor 3 | −1.737 | 0.0108 | |
| IRF3 | Interferon regulatory factor 3 | −0.806 | 0.0470 | |
| AKT1 | AKT serine/threonine kinase 1 | −0.805 | 0.0038 | |
| p53 signaling pathway | CCNB2 | Cyclin B2 | 1.222 | 0.0086 |
| STRAP | Serine/threonine kinase receptor associated protein | 0.248 | 0.0210 | |
| CDK1 | Cyclin dependent kinase 1 | 0.849 | 0.0056 | |
| CHEK1 | Checkpoint kinase 1 | 0.875 | 0.0296 | |
| CHEK2 | Checkpoint kinase 2 | 0.810 | 0.0033 | |
| CCNE1 | Cyclin E1 | 1.228 | 0.0015 | |
| GADD45A | Growth arrest and DNA damage inducible alpha | 1.675 | 0.0325 | |
| GADD45B | Growth arrest and DNA damage inducible beta | 0.745 | 0.0425 | |
| CDK2 | Cyclin dependent kinase 2 | 1.264 | 0.0085 |