Table 1.

Univariate and multivariate analyses of prognostic factors in 182 cases of PDAC.

Parameter	Univariate analysis			Multivariate analysis
	HR	95%CI	P	HR	95%CI	P
Age	1.028	1.008–1.049	0.006	1.019	1.0076–1.0483	0.007
History of CP	1.161	0.5554–2.428	0.7
History of DM	1.119	0.5142–1.554	0.7
Maximum tumor diameter	1.008	0.904–1.124	0.9
Histologic grade(Grade 1,2 vs. Grades 3, 4)	1.6901	1.065–2.682	0.02	1.4087	0.9032–2.1973	0.130816
M	1.463	0.1650–2.831	0.7
N	1.236	0.7929–1.927	0.4
T	4.228	1.327–13.47	0.008	2.79	0.8745–8.898	0.08302
Primary therapy Response	0.444	0.2772–0.7113	3.00E-04	0.3865	0.2374–0.6292	0.000132
Radiation_Therapy	0.5354	0.292–0.981	3.00E-02	0.5383	0.2923–0.9910	0.046717
Gender_male	0.8174	0.545–1.226	0.3
Tumor Stage III, IV	2.506	0.7917–7.924	0.1
Alcohol exposure yes	1.186	0.7657–1.838	0.1
S100A16 expression	1.647	1.24–2.189	6.00E−04	0.632	0.383–1.044	0.073
Risk_score	2.253	1.24–2.189	1.601–3.169	3.5053	2.0038–6.1318	1.10E−05