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Molecular mechanisms of NLRP3 activation in drug-induced cardiotoxicity. drp1, dynamin-related protein 1; ER stress, endoplasmic reticulum stress; HSP22, heat shock protein 22; IGF2BP1, insulin like growth factor 2 mRNA binding protein 1; lncRNA TINCR, terminal differentiation-induced non-coding RNA; NOX, nicotinamide adenine dinucleotide phosphate oxidase; TMAO, Trimethylamine N-oxide.
