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. 2021 Apr 14;118(16):e2019116118. doi: 10.1073/pnas.2019116118

Fig. 4.

Fig. 4.

Histogram of the expected number of genes that fall into the top 10% CCRs over 100,000 randomly drawn sets of 27 genes. The empirical data are demarcated by the blue line (P = 0.025). The contingency table shows the count of genes classified as to whether all exons overlap an ROH (“ROH”) and whether any exons overlap a CCR (“CCR”). There is a 2.94-fold enrichment of genes with at least one exon without an ROH (“non-ROH” genes) in CCRs (P = 0.041) relative to genes where all exons overlap an ROH.