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. 2021 Apr 21;218(6):e20200303. doi: 10.1084/jem.20200303

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© 2021 Lanz et al.

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Figure S5. — A high dose of an HA head-specific antibody can protect WT and IFITM3 knockout mice from disease. (a) Lungs from three IAV-infected WT and three IAV-infected IFITM3 knockout mice were harvested, homogenized, and analyzed by Western blot for IFITM3 and viral NP levels. (b) Morbidity upon lethal PR8 challenge (80 PFU) in IFITM3 knockout and WT mice 4 h after administration of a high dose of a PR8 HA head-specific antibody (2.5 mg/kg) or a control antibody. Error bars represent SD.