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. 2021 Apr 12;12:645395. doi: 10.3389/fendo.2021.645395

Table 2.

Rates of unilateral PA patients without apparent adrenal tumors in each parameter classified by quartile.

Parameter Rates of Unilateral PA (%) P
Age, years <43 10.9 0.022*
44-51 9.6
52-60 15.2
≥61 14.7
HT duration, years <1 5.5 <0.001*
1-3 7.0
4-9 12.3
≥10 23.7
Creatinine, mg/dL <0.6 8.1 <0.001*
0.6-0.70 8.2
0.71-0.83 12.3
≥0.84 21.6
Serum K+, mEq/l <3.6 34.2 <0.001*
3.6-3.8 10.7
3.9-4.0 7.4
≥4.1 5.1
ARR, pg/ml per ng/ml/h <298 6.0 <0.001*
298-442 7.1
443-742 11.2
≥743 26.2
PAC, pg/ml <123 2.6 <0.001*
123-161 9.5
162-225 12.6
≥226 25.4

Cuzick’s nonparametric test was performed to assess trends across ordered groups. Asterisks (*) indicate significant differences (P <0.05). ARR, aldosterone-to-renin ratio; HT, hypertension; PA, primary aldosteronism; and PAC, Plasma aldosterone concentration.