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. 2021 Apr 12;12:659625. doi: 10.3389/fimmu.2021.659625

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Copyright © 2021 Abbas, Reville, Jiang, Yang, Reuben, Im, Little, Sinson, Chen, Futreal and Garcia-Manero

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Diversity TCR metrics in healthy and pre-treatment MDS bone marrows. (A) Richness and (B) rarefaction analysis between healthy and pre-treatment MDS bone marrows for estimation of diversity. (C) Distribution of CDR3 lengths in healthy and pre-treatment MDS bone marrows. (D) Simpson clonality index as measurement of degree of clonality. (E) Relative abundance of the different clonotype groups based on the frequency of clonotype. (F) Barplot representation of the relative abundance measurements in (E). *p < 0.05.