Table 2.
Clinical and biochemical features of patients with Laron Syndrome.
| Age | Gender | Birth weight (kg) | Birth length (cm) | Weight SDS | Height SDS | Basal GH (ng/ml) | Peak GH (ng/ml) | IGF-1 (ng/ml) | IGF-1 SDS | IGFBP3 (mg/L) | Bone age retardation (months) | GH treatment and duration | ΔHeight after rhGH (cm) | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P1 | 7.6 | Male | 2.65 | Unknown | -2.96 | -5.49 | 15.44 | 23.36 | 32 | -3.0 | 1.2 (1.3~5.6) | 12 | Yes, 0.053mg/kg/d for 2 months | 3.3 |
| P2 | 3.5 | Male | 3.15 | 46 | -2.93 | -2.80 | 2.10 | Unknown | <25 | -3.0 | Unknown | 6 | No | |
| P3 | 14.3 | Male | Unknown | Unknown | -2.61 | -6.71 | 9.60 | 31.7 | <25 | -3.0 | 0.6 (0.7~3.9) | 28 | No | |
| P4 | 4.8 | Male | 3.20 | 51 | -1.82 | -3.95 | 1.59 | >33.80 | <25 | -3.0 | 1.14 (1.0~4.7) | 24 | Yes, 0.057mg/kg/d for 32 months | 17.8 |
SDS, standard deviation score; rhGH, recombinant human growth hormone.