Table 4.
Characteristic | G-CSF | PEG-G-CSF | P |
---|---|---|---|
Number | 42 | 83 | |
Patient age, median(range) | 30 (8, 55) | 29 (10, 62) | .782 |
Patient gender, male/female, n | 23/19 | 51/32 | .473 |
Diagnosis | .445 | ||
AML/high-risk MDS, n | 21 | 34 | |
ALL, n | 6 | 23 | |
NHL/ANKL/CAEBV, n | 7 | 10 | |
CML/CMML, n | 2 | 2 | |
SAA, n | 6 | 14 | |
Donor age, median(range) | 34.5 (8, 59) | 32 (13, 56) | .280 |
Donor gender, male/female, n | 31/11 | 61/22 | .970 |
Donor type, n | <.001 | ||
Matched sibling donor | 19 | 21 | |
Mismatched related donor | 14 | 62 | |
Matched unrelated donor | 9 | 0 | |
Donor-recipient sex match, n | .662 | ||
Male–male | 18 | 36 | |
Male–female | 13 | 25 | |
Female–male | 5 | 15 | |
Female–female | 6 | 7 | |
Donor–recipient relation, n | <.001 | ||
Sibling–sibling | 24 | 39 | |
Parent–child | 9 | 27 | |
Child–parent | 0 | 17 | |
Others | 9 | 0 | |
ABO matched, n | .261 | ||
Matched | 25 | 44 | |
Major mismatched | 8 | 19 | |
Minor mismatched | 4 | 16 | |
Bidirect mismatched | 5 | 4 | |
Disease status at HSCT, n* | .910 | ||
CR | 27 | 55 | |
PR | 6 | 13 | |
Conditioning regimen, n | .759 | ||
Bu-Cy-based regimen | 31 | 56 | |
TBI-Cy-based regimen | 5 | 13 | |
Flu-Cy-ATG regimen | 6 | 14 | |
GVHD prophylaxis, n | .008 | ||
CsA+MTX | 23 | 22 | |
CsA+MTX+MMF | 14 | 46 | |
FK506+MTX+MMF | 5 | 15 |
*: n = 101, which did not include SAA and CAEBV.
HSCT, hematopoietic stem cell transplantation; CsA, cyclosporin A; MTX, methotrexate; MMF, mycophenolate mofetil.