Table 6.
Multivariate analysis for OS, GRFS and Relapse.
| Outcome | Variable | Subtype | Hazard ratio (95%CI) | p value |
|---|---|---|---|---|
| Overall survival | Patient age | <45-y old ≥45-y old |
1.657 (0.520–5.280) | 0.600 |
| Donor type | HLA matched HLA mismatched |
1.172 (0.448–3.069) | 0.638 | |
| Th/Ts | <1.16 ≥1.16 |
1.644 (0.504–5.360) | 0.296 | |
| M-MDSC,106/kg | >20.82 ≤20.82 |
2.914 (1.148–7.398) | 0.024 | |
| MDSC/Th | >0.90 ≤0.90 |
2.160 (0.788–5.918) | 0.106 | |
| GRFS | Patient age | <45-y old ≥45-y old |
1.243 (0.477–3.239) | 0.674 |
| Donor type | HLA matched HLA mismatched |
1.079 (0.469–2.480) | 0.897 | |
| Th/Ts | <1.16 ≥1.16 |
1.648 (0.717–3.787) | 0.188 | |
| M-MDSC,106/kg | >20.82 ≤20.82 |
1.146 (0.355–3.701) | 0.276 | |
| G-MDSC,106/kg | >104.1 ≤104.1 |
1.230 (0.364–4.156) | 0.653 | |
| M-MDSC/T | >0.15 ≤0.15 |
0.889 (0.147–5.378) | 0.338 | |
| M-MDSC/Ts | >0.39 ≤0.39 |
1.527 (0.323–7.210) | 0.382 | |
| MDSC/Ts | >1.38 ≤1.38 |
2.187 (1.009–4.736) | 0.047 | |
| Relapse | Patient age | <45-y old ≥45-y old |
0.717 (0.088–5.844) | 0.116 |
| Donor type | HLA matched HLA mismatched |
2.318 (0.589–9.118) | 0.640 | |
| Disease status | CR PR |
1.170 (0.316–4.335) | 0.186 | |
| M-MDSC, 106/kg | >20.82 ≤20.82 |
1.510 (0.368–6.192) | 0.209 | |
| G-MDSC,106/kg | >104.1 ≤104.1 |
1.133 (0.292–4.402) | 0.198 |