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. 2021 Mar 9;3(2):fcab024. doi: 10.1093/braincomms/fcab024

Table 1.

Fetal pH, blood gases and metabolites from the 21-day recovery groups

Group Baseline UCO
(5 min)
UCO
(17 min)
+2 h +4 h +6 h +1 day +3 days +7 days +14 days +21 days
pH Sham 7.36 ± 0.01 7.36 ± 0.01 7.36 ± 0.01 7.36 ± 0.01 7.35 ± 0.01 7.35 ± 0.01 7.35 ± 0.01 7.34 ± 0.01 7.35 ± 0.01 7.34 ± 0.01 7.33 ± 0.01
UCO 7.35 ± 0.01 7.03 ± 0.01* 6.84 ± 0.01* 7.29 ± 0.02* 7.38 ± 0.01 7.40 ± 0.01* 7.36 ± 0.01 7.36 ± 0.01 7.36 ± 0.01 7.35 ± 0.01 7.36 ± 0.01*
paCO2 (mmHg) Sham 48.5 ± 0.7 47.1 ± 0.8 46.6 ± 0.8 47.3 ± 0.9 46.1 ± 1.1 46.7 ± 0.9 48.4 ± 0.7 48.4 ± 0.8 49.1 ± 0.8 48.6 ± 1.0 49.4 ± 1.2
UCO 50.7 ± 1.4 99.7 ± 2.6* 136.4 ± 6.0* 47.8 ± 0.8 47.7 ± 1.1 48.5 ± 0.7 46.3 ± 1.4 46.8 ± 1.5 49.2 ± 1.8 50.6 ± 1.4 48.6 ± 1.1

paO2 (mmHg)

Sham 25.6 ± 0.6 24.6 ± 0.7 24.3 ± 0.6 25.5 ± 0.7 24.9 ± 0.5 25.7 ± 0.7 26.2 ± 0.8 27.0 ± 0.7 25.3 ± 1.1 26.0 ± 1.4 22.6 ± 1.3
UCO 24.7 ± 0.8 6.6 ± 0.4* 9.5 ± 1.2* 27.2 ± 1.2 23.5 ± 1.0 25.4 ± 1.0 29.1 ± 1.0* 31.1 ± 1.2* 29.4 ± 1.5* 28.4 ± 1.2 26.5 ± 1.8

Hct (%)

Sham 27.2 ± 0.7 26.2 ± 0.8 26.1 ± 0.9 26.7 ± 0.7 25.4 ± 0.7 25.9 ± 0.9 26.9 ± 0.8 29.4 ± 1.4 31.6 ± 1.8 31.3 ± 1.3 31.4 ± 0.8
UCO 26.2 ± 0.7 27.8 ± 1.1 28.2 ± 0.8 28.1 ± 0.7 27.4 ± 0.5* 27.7 ± 0.8 29.0 ± 0.5* 30.2 ± 2.2 33.6 ± 3.7 35.2 ± 4.4 30.5 ± 1.2

O2ct (mmol/l)

Sham 3.6 ± 0.1 3.4 ± 0.1 3.3 ± 0.2 3.6 ± 0.1 3.2 ± 0.1 3.4 ± 0.2 3.7 ± 0.2 3.9 ± 0.1 3.9 ± 0.2 6.6 ± 2.7 3.3 ± 0.3
UCO 3.6 ± 0.1 0.4 ± 0.1* 0.5 ± 0.1* 4.3 ± 0.3* 3.6 ± 0.2 4.1 ± 0.2* 4.5 ± 0.1* 4.6 ± 0.2* 4.6 ± 0.2* 4.5 ± 0.2 4.2 ± 0.2*

Lactate (mmol/l)

Sham 0.9 ± 0.1 0.9 ± 0.03 0.9 ± 0.1 0.9 ± 0.0 0.9 ± 0.0 1.0 ± 0.0 0.9 ± 0.1 0.8 ± 0.04 0.9 ± 0.0 0.8 ± 0.0 1.1 ± 0.1
UCO 0.8 ± 0.1 3.9 ± 0.2* 6.2 ± 0.3* 4.8 ± 0.7* 3.0 ± 0.5* 2.1 ± 0.2* 1.5 ± 0.2* 0.9 ± 0.1 0.7 ± 0.0* 0.8 ± 0.0 0.8 ± 0.0
Glucose (mmol/l) Sham 1.1 ± 0.1 1.0 ± 0.04 1.0 ± 0.1 1.2 ± 0.1 1.1 ± 0.1 1.2 ± 0.1 1.1 ± 0.1 1.0 ± 0.1 1.0 ± 0.1 0.8 ± 0.1 0.8 ± 0.1
UCO 1.0 ± 0.1 0.4 ± 0.1* 0.6 ± 0.1* 1.3 ± 0.1 1.3 ± 0.1 1.4 ± 0.1* 1.4 ± 0.1* 1.1 ± 0.1 0.9 ± 0.1 0.9 ± 0.1 0.9 ± 0.0

paCO2, arterial partial pressure of carbon dioxide; paO2, arterial partial pressure of oxygen; Hct, haematocrit; O2ct; arterial oxygen content.

*

P < 0.05 sham versus UCO. Data are means ± SEM.