Table 3.

Patterns of macroscopic WMI observed in the 21d-UCO group

Number of foetuses	Primary features	Secondary features
4	Marked white matter atrophy and ventriculomegaly	One foetus developed focal cystic white matter lesions in the temporal lobe and the second parasagittal gyrus of the parietal lobe
2	Extensive cystic white matter lesions in the temporal lobe	No ventriculomegaly
1	Focal cystic white matter lesions in the temporal lobe and first parasagittal gyrus of the parietal lobe	No ventriculomegaly or reduction in white matter area
2	No cystic lesions or ventriculomegaly	Moderate reduction in white matter area