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. 2021 Apr 18;13(4):1349. doi: 10.3390/nu13041349

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Effect of GJ on AD-related symptoms in ABX-induced AD mice. (A) Experimental scheme of animal study. Time-dependent changes in (B) body weight and (C) food intake per day (g/mice) were measured. Vehicle: normal control group; ABX: antibiotic cocktail-administered group. (D) Visual observation of dorsal skin was made and (E) the dorsal thickness was measured using a Vernier caliper. (F) The skin severity score was visually evaluated between 1 and 10 points. Vehicle: normal control group; ABX: antibiotic cocktail-administered group; DNCB: DNCB-applied group; ABX+DNCB: antibiotic cocktail-administered and DNCB-applied group; A+D+GJ: antibiotic cocktail-administered and DNCB-applied group fed with GJ. **** p < 0.001.