Table 15.
Cytotoxic activity of Thymus algeriensis essential oil against human cell lines (% of inhibition cells ± SEM).
| Sample Code (Cell Line) |
Concentration (µg/mL) | LC50 (μg/mL) |
LC90 (g/mL) |
Doxorubicin LC50 (μg/mL) |
DMSO at 100 ppm |
|||
|---|---|---|---|---|---|---|---|---|
| 100 | 50 | 25 | 12.5 | |||||
| HCT116 | 100 a | 71.37 a | 22.36 a | 4.77 a | 39.8 | 59.6 | 37.6 | 1% |
| HePG2 | 44.2 b | 0.0 b | 0.0 b | 0.0 b | >100 | >100 | 21.6 | 1% |
| HSD0.05 | 5.5 | 4.0 | 1.3 | 0.3 | ||||
Letter indicators at averages determine the so-called homogeneous groups (statistically homogeneous). Every value represents the mean percentage of inhibition cells of three replicates ±SEM (mean of standard error). LC50: Lethal concentration of the sample that causes the death of 50% of the cells in 48 h. LC90: Lethal concentration of the sample that causes the death of 90% of the cells in 48 h. HePG2 (human hepatocellular carcinoma cell line) HCT116 (colon cell line).