Table 1.

General overview of miRNAs involved in quiescent satellite cells and proliferative myoblast states. Arrows indicate miRs that are expressed (↑) or downregulated (↓) within each cell stage.

microRNAs	Targets	Function	References
Quiescent Satellite Cell State
miR-195/497↑	Cdc25a/b and Ccnd2	Promotes SCs quiescence by inducing cell cycle arrest	[45]
miR-489↑	Dek	Regulates SCs quiescence	[46]
miR-31↑	Myf5	Prevents MYF5 protein accumulation and premature activation of SCs	[47]
miR-708↑	Tns3	Regulates quiescence and self-renewal by active repression of SCs migration	[48]
Proliferative Myoblast State
miR-27 ↑	Mstn	Enhances and/or promotes myoblast proliferation	[51]
miR-17, miR-20a, and miR-92a↑	Enh1	Enhance and/or promotes myoblast proliferation	[53]
miR-664↑ and miR-133↑	Srf	Enhances and/or promotes myoblast proliferation by inducing cell cycle genes expression	[54,55]
miR-133↓	Sp1	Inhibit myoblast proliferation	[57]
miR-1↓	Ccnd1	Inhibit myoblast proliferation	[57]
miR-195 and miR-497↓	Igf1r, Insr, Ccne1 and Ccnd2	Inhibit myoblast proliferation	[61]
miR-128a↓	Irs1 and Pik3r1	Inhibits myoblast proliferation	[67]
miR-487b↓	Irs1	Inhibits myoblast proliferation	[68]
miR-16↓	Foxo1 and Bcl2	Inhibits myoblast proliferation and promotes myoblast apoptosis	[71]
miR-15b, miR-23b, miR-106b, and miR-503↓	Ccnd1 and Ccnd2	Inhibits myoblast proliferation	[72]
miR-106b↓	Myf5	Prevents commitment to myogenic cell fate	[72]