AD |
Alzheimer disease |
ALS |
amyotrophic lateral sclerosis |
APP |
amyloid beta precursor protein |
BDNF |
brain-derived neurotrophic factor |
CRM1 |
Chromosome region maintenance 1 protein |
DPRs |
di-peptide repeat proteins |
ER |
endoplasmic reticulum |
FG repeats |
phenylalanine-glycine repeats |
FISH |
fluorescence in situ hybridization |
FUS |
fused in sarcoma |
FTD |
frontotemporal dementia |
hnRNPs |
heterogeneous nuclear ribonucleoproteins |
HAP1 |
huntingtin associated protein 1 |
HD-RAN |
HD repeat-associated non-AUG translation |
HTT |
Huntingtin |
INM |
inner nuclear membrane |
Kap |
Karyopherin |
MAP2 |
microtubule-associated protein 2 |
MAPT |
microtubule-associated protein tau |
mHTT |
mutant huntingtin |
MNDs |
motor neuron diseases |
mRNP |
messenger ribonucleoprotein |
NCT |
nucleocytoplasmic transport |
NDs |
neurodegenerative diseases |
NE |
nuclear envelope |
NEDD8 |
neural precursor cell-expressed and developmentally down-regulated 8 |
NES |
nuclear export sequence |
NFTs |
neurofibrillary tangles |
NLS |
nuclear localization sequence |
NMJ |
neuromuscular junction |
NPC |
nuclear pore complex |
NTR |
nuclear transport receptors |
Nups |
nucleoporins |
O-GlcNAc |
O-linked N-acetylglucosamine |
ONM |
outer nuclear membrane |
PSEN1 |
presenilin1 |
PY-NLSs |
proline-tyrosine amino acid pairing |
RAN |
Ras-related nuclear protein |
RanBP1 |
Ran-binding protein 1 |
RanBP2/Nup358 |
Ran-binding protein 2/nucleoporin 358 |
RanBP3 |
Ran-binding protein 3 |
RanGAP |
Ran GTPase-activating protein |
RanGEF |
Ran Guanine nucleotide Exchange Factor |
RBPs |
RNA-binding proteins |
RCC1 |
regulator of chromosome condensation 1 |
RNPs |
ribonucleoproteins |
RNS |
Reactive nitrogen species |
SFPQ |
splicing factor proline- and glutamine-rich |
SOD1 |
superoxide dismutase-1 |
SORT1 |
sortilin |
TARDBP |
transactive response DNA-binding protein |
XPO1 |
Exportin-1 |