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. 2021 Apr 16;26(8):2318. doi: 10.3390/molecules26082318

Scheme 2.

Scheme 2

Mechanistic hypothesis for the formation of polycyclic heterocycles 2 by Zn2+‒mediated sequential deprotection ‒ 6-endo-dig heterocyclization of N-Boc-alkynylbenzimidazoles 1.