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. 2021 Apr 19;18(8):4331. doi: 10.3390/ijerph18084331

Table 6.

Health outcomes associated with dumpsites and open burning.

Study Location Study Design Main Findings Ref.
Mortality
Brazil Cohort study (retrospective) Standardized mortality ratios (SMRs) for areas of 2 km around the solid waste landfill sites (95% CI):
- bladder cancer: 0.98 (0.79, 1.21)
- liver cancer: 1.00 (0.86, 1.16)
- leukaemia in adults: 0.92 (0.77, 1.10)
- leukaemia in children: 0.84 (0.54, 1.31)
Standardized mortality ratios (SMRs) for areas of 2 km around the solid waste landfill sites (95% CI):
- congenital malformation: 0.86 (0.72, 1.03)
[59]
Adverse birth and neonatal outcomes
Alaska Cohort study (retrospective) Adjusted odds ratios (95% CI) describing the relations between low and high hazard exposure categories and incidence of low and very low birth weight, preterm birth, and intrauterine growth retardation:
- low birth weight: 2.06 (1.28, 3.32), p < 0.05 a
- low birth weight adjusted for gestation: 2.20 (1.26, 3.85), p < 0.05 a
- very low birth weight: 1.17 (0.37, 3.67)
- preterm birth: 1.24 (0.89, 1.74)
- intrauterine growth retardation: 3.98 (1.93, 8.21), p < 0.05 a
[58]
Alaska Cohort study (retrospective) Adjusted rate ratios (95% CI) describing the relationships between lower and higher hazard exposure categories and incidence of foetal and neonatal death and congenital anomalies:
- all deaths: 0.65 (0.34, 1.27)
- foetal deaths: 0.75 (0.28, 1.99)
- neonatal deaths: 0.55 (0.22, 1.38)
- all congenital anomalies (CA), (listed separately in the categories below): 1.37 (0.92, 2.04)
- central nervous system CA: 2.36 (0.37, 14.71)
- circulatory/respiratory CA: 1.42 (0.39, 5.42)
- gastrointestinal CA: 0.58 (0.14, 2.40)
- urogenital CA: 2.71 (0.67, 10.95)
- musculoskeletal/integumental CA: 1.61 (0.79, 3.29)
- others CA: 1.38 (0.77, 2.39)
- multiple CA: 1.33 (0.34, 5.20)
[60]
Gastroenteritis
Swaziland Cross-sectional study Diseases which affected residents:
- diarrhoea: 16% of closer residents vs. 5% of further away residents
Reasons for hospitalization among the interviewed:
- diarrhoea: 16% of closer residents vs. 26% of further away residents
- cholera: 12% of closer residents vs. 0% of further away residents
[20]
Nigeria Cross-sectional study Diseases which affected residents b:
- cholera and diarrhoea: 10 closer households vs. 5 further away households reported 1–2 cases; 0 closer households vs. 0 further away households reported 3–4 cases; 0 closer households vs. 0 further away households reported at least 5 cases
[61]
Sierra Leone Cross-sectional study Diseases which affected residents c:
- diarrhoea: about 10% of closer residents vs. about 12% of further away residents
- cholera: about 11% of closer residents vs. about 15% of further away residents
[62]
Ghana Cross-sectional study Diseases which affected residents d:
- cholera: (a) 67%; (b) 33%; (c) 0% (out of a total of 6 people affected)
- typhoid fever: (a) 75%; (b) 25%; (c) 0% (out of a total of 12 people affected)
[63]
Vector-borne diseases
Swaziland Cross-sectional study Diseases which affected residents:
- malaria: 36% of closer residents vs. 13% of further away residents
Reasons for hospitalization among the interviewed:
- malaria: 44% of closer residents vs. 18% of further away residents
[20]
Nigeria Cross-sectional study Diseases which affected residents b:
- malaria: 20 closer households vs. 24 further away households reported 1–2 cases; 4 closer households vs. 8 further away households reported 3–4 cases; 0 closer households vs. 1 further away households reported at least 5 cases
[61]
Sierra Leone Cross-sectional study Diseases which affected residents c:
- malaria: 40% of closer residents vs. 35% of further away residents
[62]
Ghana Cross-sectional study Diseases which affected residents d:
- malaria: (a) 73%; (b) 25%; (c) 2% (out of a total of 103 people affected)
[63]

ap < 0.05. The authors indicated the p-value when it was lower than 0.05; b The authors categorized counts of reported cases into groups for each health outcome and then used a chi-square test to test for differences. No significant differences were found; c The % is an approximate value taken from a figure in the article; d Comparing three temporal distances between people and disposal sites: (a) less than 5 min, (b) 5–10 min, (c) 11–15 min.