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The role of immune cells in tumor growth. CD4+, CD8+, or natural killer (NK) 1.1+ cells were depleted by monoclonal antibodies and macrophages by carrageenan in mice bearing TC-1-induced tumors (A) or TC-1/dCD80-1-induced tumors (B). Statistical analysis indicates a comparison with the phosphate-buffered saline (PBS)-treated group. Bars indicate ±SEM; * p < 0.05, ** p < 0.01, **** p < 0.0001.
