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. 2021 Apr 19;10(4):621. doi: 10.3390/antiox10040621

Figure 1.

Figure 1

Effect of exercise and the combined action of exercise and catechin treatment on motor coordination (A) and the evolution of body weight (B) in old rats (18 months). (A) Bars represent the mean ± SEM of the time spent (sec) on the rotating wheel, using the rotarod test, of animals subjected to a daily physical exercise program (Exerc, n = 7) and animals subjected to the combined effect of a daily physical exercise program and intraperitoneal administration of catechin (20 mg/kg/day, n = 7; Exerc + Cat,) compared to control animals (n = 7). Two-way repeated measures ANOVA detected a significant effect for the treatment (F(2,54) = 19.6, p < 0.0001), the subjects (F(18,54) = 4.6, p < 0.0001), the age (F(2,54) = 78, p < 0.0001) and the interaction (F(4,54) = 21.90, p < 0.0001). B) Dots represent the mean ± SEM of the body weight (g) of the same animals. Two-way repeated measures ANOVA detected a significant effect for the subjects (F(18,72) = 33.12, p < 0.0001), the age (F(3,72) = 88.50, p < 0.0001) and the interaction (F(6,72) = 12.46, p < 0.0001), but not for the treatment (F(2,72) = 2.451, p = 0.1145). * p < 0.05, ** p < 0.01, *** p < 0.001 when compared to the control group; ### p < 0.001 comparing the values obtained by each group before and after performing the treatments (two-way ANOVA followed by Bonferroni).