Table 1.
Description of N1 mutant constructs.
| Construct Name | Description of Mutation |
|---|---|
| AA82-388 | Neuraminidase head only |
| AA46-388 | Neuraminidase head + 36 aa of stalk domain |
| AA46-388 (C49A) | Monomeric control |
| AA46-388 (T48C) | Cysteine mutation in the stalk at position 48 |
| AA46-388 (N50C) | Cysteine mutation in the stalk at position 50 |
| AA46-388 (T48C + N50C) | Cysteine double-mutation in the stalk at position 48 and 50 |
| AA46-388 (A76C) | Cysteine mutation in the stalk at position 76 |
| AA46-388 (Q78C) | Cysteine mutation in the stalk at position 78 |
| AA46-388 (V81C) | Cysteine mutation in the stalk at position 81 |
| AA46-388 (VASP) | Neuraminidase head + 36 aa of stalk domain + VASP domain |
| AA46-388 (W61C) | Cysteine mutation in the stalk at position 61 |