Table A7.
ClotPro® reagents.
| Assay | Reagent | Description | Heparin Neutralization |
|---|---|---|---|
| IN-test | Ellagic acid | Intrinsic pathway screening test | No |
| HI-test | Ellagic acid + Heparinase | Intrinsic pathway screening test with heparinase | Yes |
| EX-test | Recombinant tissue factor + Polybrene | Rapid overview of the coagulation process | Yes |
| AP-test | Tissue factor + Aprotinin + Polybrene | Exploration of the fibrinolysis by comparison with the EX-test results | Yes |
| tPA-test | Recombinant tissue factor + Recombinant tPA + Polybrene | Exploration of the fibrinolysis by comparison with the EX-test results | Yes |
| FIB-test | Recombinant tissue factor + Cytolochalasin D + Abciximab + Polybrene | Functional detection of the fibrinogen level after dual platelet inhibition by cytochalasin D and abciximab | Yes |
| RVV-test | Reagent derived from Russell viper venom | Detection of factor Xa inhibitors (LMWH, DOAC) | No |
| ECA-test | Ecarin + Polybrene | Detection of direct thrombin antagonists | Yes |
| NA-test | None | Non-activated test for the exploration of non-activated coagulation in citrated blood | No |
Abbreviations: LMWH: Low molecular weight heparin; UFH: unfractionated heparin; DOAC: Direct oral anticoagulant.