Table 1.

Function of genes involved in neonatal-onset epilepsies/EE and MD.

Functional Role	Gene Name
Channelopathies	CACNA1E, KCNQ2, SCN2A, SCN8A
ATPase	ATP1A3
Synaptopathies	AP3B2, DNM1, STXBP1, VAMP2, SYNJ1
G protein transduction	GNAO1
Transcription factors	FOXG1
Transcription regulators	CDKL5, SMC1A, PURA
Neuronal connectivity/signal transduction	PCDH12
Ubiquitination	RHOBTB2
Receptors	GABRA1, GABRB2, GABRB3, GABRG2, GRIA2, GRIN2B
Enzymes	WWOX
Growth factors	FHF1
Transporters	SLC13A5