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. 2021 Apr 19;13(4):1366. doi: 10.3390/nu13041366

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Analysis of the tryptophan metabolism in adult morbid obese female patients two weeks before and six months after vertical sleeve gastrectomy (VSG, n = 32). (A) Evolution of anthropometric parameters. (B) Effect of VSG on the plasma tryptophan (Trp) and kynurenine (Kyn) levels. (C) Correlations between the orosensory linoleic acid (LA) perception thresholds determined using the 3-ascending force-choice test and plasma Kyn levels in patients displaying an improvement of oral LA perception (i.e., reduction of LA perception threshold after VSG) and unresponsive patients. (D) Plasma C-reactive protein (CRP) levels. ns, non-significant; * p < 0.05; ** p < 0.01; *** p < 0.001.