Table 3.
Pairwise comparison of groups with IUGR, PE, SGA, and control group N by expression level of miRNA and mRNA obtained in RT-PCR.
| miRNA or mRNA | Groups to Be Compared 1 | p-Value | |
|---|---|---|---|
| IUGR < 34 | IUGR > 34 | ||
| hsa-miR-1-3p | 5.58 (4.71, 6.82) | 7.04 (6.28, 8.9) | 0.0374 |
| hsa-miR-128-3p | 6.9 (5.84, 7.23) | 7.87 (6.98, 8.28) | 0.0268 |
| YWHAZ | 8.76 (8.53, 8.92) | 8.07 (7.49, 8.39) | 0.0268 |
| ANXA2 | 1 (0.57, 1.21) | 0.66 (0.18, 0.77) | 0.0374 |
| FBN1 | 3.73 (3.28, 3.95) | 2.99 (2.58, 3.42) | 0.0439 |
| PE < 34 | PE > 34 | ||
| DSTN | 6.84 (6.68, 7.13) | 7.46 (7.29, 7.49) | 0.0026 |
| FGA | 11.07 (9.56, 13.47) | 8.29 (7.3, 9.52) | 0.0221 |
| MYH11 | 8.52 (8.26, 8.92) | 9.39 (9.13, 9.83) | 0.0098 |
| MYL6 (tr.var.1) | 3.62 (3.46, 3.8) | 4.01 (3.92, 4.11) | 0.0008 |
| MYL6 (tr.var.2) | 3.57 (3.34, 3.72) | 4.17 (3.62, 4.38) | 0.0358 |
| IUGR > 34 | N > 34 | ||
| hsa-miR-1-3p | 7.04 (6.28, 8.9) | 5.37 (3.64, 5.96) | 0.0221 |
| hsa-miR-140-3p | 0.08 (−0.4,0.48) | −0.88 (−1.63, −0.36) | 0.0449 |
| hsa-miR-15b-5p | 2.12 (1.64, 2.46) | 0.77 (0.27, 0.92) | 0.0008 |
| hsa-miR-199a-3p | 5.21 (4.71, 5.79) | 3.89 (2.69, 4.18) | 0.0037 |
| hsa-miR-199b-3p | 5.26 (4.75, 5.7) | 3.58 (2.59, 4.27) | 0.0098 |
| hsa-miR-28-3p | 5.88 (5.53, 6.75) | 4.33 (4.01, 4.8) | 0.0001 |
| hsa-miR-30c-5p | 5.72 (5.56, 6.42) | 4.04 (2.75, 4.6) | 0.0026 |
| hsa-miR-654-3p | 10.85 (9.52, 11.91) | 9.38 (8.49, 9.72) | 0.0449 |
| VIM | 1.06 (0.94, 1.31) | 1.47 (1.39, 1.75) | 0.0221 |
| ANXA2 | 0.66 (0.18, 0.77) | 0.85 (0.81, 1.13) | 0.0130 |
| FGA | 8.59 (5.94, 11.9) | 13.48 (12.06, 17.19) | 0.0098 |
| MYL 6 tr.v.1 | 3.84 (3.5, 4.09) | 4.06 (3.9, 4.33) | 0.0373 |
| MYL 6 tr.v.2 | 3.62 (3.29, 4.1) | 4.03 (3.67, 4.06) | 0.0498 |
| YWHAZ | 8.07 (7.49, 8.39) | 8.7 (8.08, 9.18) | 0.0414 |
| FBN1 | 2.99 (2.58, 3.42) | 3.28 (2.82, 3.78) | 0.0374 |
| SGA > 34 | N > 34 | ||
| FGA | 8.67 (7.53, 12.52) | 13.48 (12.06, 17.19) | 0.0229 |
| MYL 6 tr.v.1 | 3.67 (3.54, 4.11) | 4.06 (3.9, 4.33) | 0.0274 |
| hsa-miR-654-3p | 9.74 (9.06, 12.25) | 9.38 (8.49, 9.72) | 0.0269 |
| hsa-miR-15b-5p | 1.09 (0.95, 1.39) | 0.77 (0.27, 0.92) | 0.0453 |
| hsa-miR-185-3p | 7.87 (7.23, 8.16) | 6.73 (6.36, 7.49) | 0.0302 |
| hsa-miR-140-3p | 0.06 (−0.2, 0.43) | −0.88 (−1.63, −0.36) | 0.0189 |
| PE > 34 | N > 34 | ||
| hsa-miR-30c-5p | 5.82 (4.95, 6.36) | 4.04 (2.75, 4.6) | 0.0379 |
| hsa-miR-654-3p | 9.89 (9.27, 10.99) | 9.38 (8.49, 9.72) | 0.0494 |
| hsa-miR-185-3p | 7.88 (7.45, 8.2) | 6.73 (6.36, 7.49) | 0.0433 |
| FGA | 8.29 (7.3, 9.52) | 13.48 (12.06, 17.19) | 0.0023 |
| FLNA | 7.85 (7.27, 7.87) | 8.13 (7.63, 8.29) | 0.0498 |
| YWHAZ | 8.02 (7.76, 8.43) | 8.7 (8.08, 9.18) | 0.0493 |
| MYH11 | 9.39 (9.13, 9.83) | 8.32 (7.77, 8.96) | 0.0281 |
1 Data are presented as a median (Me) of the ΔCt values and quartiles Q1 and Q3 in the Me (Q1; Q3) format with an indication of the statistical significance (p) using the Mann–Whitney test.