Figure 3.
Comparison of DHB and norharmane matrices. (a) Number of lipid ions detected in all MSI datasets from all patients, for MSI datasets acquired using DHB and norharmane matrices (mean ± SD, two-tail paired t-test, ***: p < 0.001, n = 6). (b) Explained variance of the first ten PCs (mean ± SD, n = 6). (c) Venn diagram of the lipid ions in common between all MSI datasets acquired with DHB and norharmane. (d) Score images of the first 3 PCs, k-means clustering (7 clusters), annotated regions and histological images for the same carotid plaque. Annotated regions are calcification (purple), hemorrhage (brown), lipid-necrotic core (black), collagen (yellow), macrophages (orange), outer VSMCs (cyan) and inner VSMCs (green).
