| ACE2 | angiotensin-converting enzyme 2 |
| ADs | autoimmune diseases |
| ADAP | adhesion and degranulation-promoting adapter protein |
| AIRE | autoimmune regulator |
| APCs | antigen-presenting cells |
| APECED | autoimmune polyendocrinopathy candidiasis ectodermal dystrophy |
| Bcl-6 | B-cell lymphoma 6 |
| βgal | β-galactosidase |
| BL | Burkitt’s lymphoma |
| Breg | regulatory B cells |
| BTLA | B and T lymphocyte attenuator |
| CFA | complete Freund’s adjuvant |
| CMV | cytomegalovirus |
| COVID-19 | coronavirus disease 2019 |
| CTLs | cytotoxic T lymphocytes |
| CTLA-4 | cytotoxic T-lymphocyte-associated protein 4 |
| CTX | cyclophosphamide |
| CVID | common variable immunodeficiency |
| CXCR5 | C-X-C chemokine receptor type 5 |
| DCs | dendritic cells |
| DCLRE1C | deoxyribonucleic acid cross-link repair 1C |
| DMARD | disease-modifying anti-rheumatic drug |
| EAU | experimental autoimmune uveoretinitis |
| EBNA1 | Epstein–Barr nuclear antigen 1 |
| EBV | Epstein–Barr virus |
| F759 | mice with a mutation in the gp130 IL-6 receptor subunit |
| FK506 | tacrolimus |
| FoxP3 | forkhead box protein transcription factor P3 |
| GAD | glutamate acid decarboxylase |
| HAART | highly active antiretroviral therapy |
| HIV | human immunodeficiency virus |
| HLA | human leukocyte antigen |
| HP | homeostatic proliferation |
| HT | Hashimoto’s thyroiditis |
| HTLV-1 | Human T-lymphotropic virus 1 |
| IFN-γ | interferon-gamma |
| IL | Interleukin |
| IL-2R | IL-2 receptor |
| IL-21R | IL-21 receptor |
| INS | insulin |
| IRIS | immune reconstitution inflammatory syndrome |
| iTreg/pTreg | peripherally-induced Treg cells |
| K/BxN | a cross between KRN TCR transgenic mice on a C57BL/6 background (K/B) and NOD mice |
| LAG-3 | lymphocyte activation gene 3 |
| LCMV | lymphocytic choriomeningitis virus |
| LIG4 | ligase 4 |
| LIP | lymphopenia-induced proliferation |
| LNs | lymph nodes |
| MHC | major histocompatibility complex class |
| MM | memory mutant |
| MTX | methotrexate |
| NK | natural killer cells |
| NKT | natural killer T cells |
| NOD | non-obese diabetic |
| nTreg/tTreg | naturally occurring thymus-derived Treg cells |
| OS | Omenn syndrome |
| PD-1 | programmed cell death protein 1 |
| Perp | p53 apoptosis effector related to PMP-22 |
| PID | primary immunodeficiency |
| PIDs | primary immunodeficiencies |
| PRRs | pattern-recognition receptors |
| pSS | primary Sjögren’s syndrome |
| PTLD | post-transplant lymphoproliferative disorder |
| PTPN2 | protein tyrosine phosphatase N2 |
| RA | rheumatoid arthritis |
| RAG1 | recombination activating gene 1 |
| RAG2 | recombination activating gene 2 |
| RIP-GP | rat insulin promoter-glycoprotein |
| RSCs | Reed-Sternberg cells |
| RTL | relative telomere length |
| RTEs | recent thymic emigrants |
| SARS-CoV-2 | severe acute respiratory syndrome coronavirus 2 |
| SCID | severe combined immune deficiency |
| SLE | systemic lupus erythematosus |
| SNP | single nucleotide polymorphism |
| SP | spontaneous proliferation |
| SS | Sjögren’s syndrome |
| STAT3 | signal transducer and activator of transcription 3 |
| T1D | type 1 diabetes |
| TCR | T cell receptor |
| Tfh | T follicular helper |
| Tfr | follicular regulatory T cells |
| TGF-β | transforming growth factor-beta |
| TGF-βRII | transforming growth factor-beta receptor 2 |
| tgfbr2 | transforming growth factor-beta receptor 2 |
| Th1 | type 1 helper cells |
| Th3 | type 3 helper cells |
| Th17 | type 17 helper cells |
| TLRs | Toll-like receptors |
| TNF-α | tumor necrosis factor-alpha |
| Tr1 | type 1 regulatory T cells |
| TRECs | T-cell receptor excision circles |
| Tregs | regulatory T cells |
| WAS | Wiskott–Aldrich syndrome |
| WASP | WAS protein |