. 2021 Apr 17;22(8):4170. doi: 10.3390/ijms22084170

Table 3.

NETs components detected in patients with different pathologies related to thrombosis.

Biomarker	Patients	Sign Correlated to the Biomarker	References
DNA	Arterial thrombotic events and diseases	Infarct size	[150,177,178,179,180,181,182,183,184,185,186,189,190]
		Stenosis grade
		Severe stroke scores
		Hypercoagulability markers
		High glucose levels
		Thrombus age
	Venous thromboembolic events	Thromboembolism extent	[187,188]
	Venous thromboembolic events	C-reactive protein	[187,188]
	Hypertension	Homocysteinemia	[193]
	Other diseases	ITP: Platelet CD62 *^†	[191]
		Behçet’s disease: Vascular involvement	[192]
		Cushing disease: ETP ratio	[194]
Nucleosomes	Arterial thrombotic events and diseases	Infarct size	[178,185,190]
		Stenosis grade
		Severe stroke scores
		High glucose levels
	Venous thromboembolic events	Thromboembolism extent	[187]
	Other diseases	Cushing disease: ETP ratio	[194]
citH3/H4	Arterial thrombotic events and diseases	Infarct size	[180,181,184,189,190]
		Stenosis grade
		Severe stroke scores ^†
		High glucose levels ^†
		Thrombus age, stabilization and growth
	Venous thromboembolic events	Lactate levels	[195]
	Other diseases	ITP: Platelet CD62 *^†	[191]
MPO	Arterial thrombotic events and diseases	Stenosis grade ^‡	[185]
	Venous thromboembolic events	C-reactive protein	[195]
	Venous thromboembolic events	D-dimer	[195]
	Hypertension	Homocysteinemia ^‡	[193]
	Other diseases	Behçet’s disease: Vascular involvement ^‡	[192]
	Other diseases	Cushing disease: ETP ratio	[194]
NE	Arterial thrombotic events and diseases	Thrombus stabilization and growth	[184]

NETs: Neutrophil extracellular traps. DNA: Desoxyribonucleic acid. citH3/H4: citrullinated histone H3/H4. MPO: Myeloperoxidase. NE: neutrophil elastase. ITP: Primary immune thrombocytopenia. CD: cluster of differentiation. ETP: Endogenous thrombin potential. * Negative correlation. ^† DNA-citH3 complexes. ^‡ DNA-MPO complexes.