Musculoskeletal measurements. (a,b) μCT analysis of mouse tibiae. (a) Percent cancellous bone volume (BV/TV, %). NL Sham (n = 12), NL PAD (n = 12), HU Sham (n = 10), and HU PAD (n = 10). * Statistically significant at p < 0.05 by nonparametric Wilcoxon all pairs test at p < 0.05. (b) Cortical thickness (Ct.Th.). NL Sham (n = 11), NL PAD (n = 12), HU Sham (n = 11), and HU PAD (n = 10). * Statistically significant at p < 0.05 by one-way ANOVA with Tukey post-hoc test. (c) Right soleus weight normalized to body weight. NL Sham (n = 12), NL PAD (n = 12), HU Sham (n = 11), and HU PAD (n = 9). * Statistically significant at p < 0.05 by one-way ANOVA with Tukey post-hoc test.