Table 5.
Frequency of genotypes and alleles of the MSX1 rs8670 and rs12532 gene polymorphism in the study and control group.
| Freq. Genotypes | Freq. Alleles | ||||
|---|---|---|---|---|---|
| MSX1 rs8670 | C/C n (%) |
C/T n (%) |
T/T n (%) |
C n (%) |
T n (%) |
| Study group n = 202 | 113 (0.56) |
74 (0.37) |
15 (0.07) |
300 (0.74) | 104 (0.26) |
| Control group n = 186 | 115 (0.62) |
60 (0.32) |
11 (0.06) |
290 (0.78) | 82 (0.22) |
| χ2 (p) OR [95% CI] |
1.44 (0.487) OR C/C:C/T = 0.80 [0.52–1.22]; OR CC:T/T = 0.72 [0.32–1.64]; OR C/T:T/T = 0.90 [0.39–2.11] |
1.46 (0.228) OR C:T = 0.82 [0.59–1.14] |
|||
| MSX1 rs12532 | A/A n (%) |
A/G n (%) |
G/G n (%) |
A n (%) |
G n (%) |
| Study group n = 203 | 110 (0.54) |
74 (0.37) |
19 (0.09) |
294 (0.72) | 112 (0.28) |
| Control group n = 186 | 99 (0.53) |
71 (0.38) |
16 (0.09) |
269 (0.72) | 103 (0.28) |
| χ2 (p) OR [95% CI] |
0.16 (0.925) OR A/A:A/G = 1.07 [0.70–1.63]; OR A/A:G/G = 0.95 [0.46–1.92]; OR A/G:G/G = 0.88 [0.42–1.84] |
0.001 (0.975) OR A:G = 1.01 [0.73–1.38] |
|||
p-statistical significance χ2 test, OR—Odds Ratio, significant OR (p < 0.05).