Table 6.
Comparison of MSX1 haplotypes between the study (Stu) and control (Con) group with statistical significance of effects (additive, dominant, and recessive); total number of haplotypes taken into account during analyses: n = 388.
|
MSX1 NM_002448.3:c.[6C > T; 276A > G] |
Frequency | Additive | Dominant | Recessive | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 1.56; df = 2; p = 0.458 (0.452) † | 1.89; df = 3; p = 0.595 (0.568) † | 0.65; df = 3; p = 0.885 (0.902) † | ||||||||
| rs8670 | rs12532 | General | Con | Stu | Score | p a | Score | p a | Score | p a |
| C | A | 0.48 | 0.50 | 0.47 | −0.97 | 0.331 (0.340) | −1.01 | 0.314 (0.306) | −0.57 | 0.569 (0.598) |
| C | G | 0.28 | 0.28 | 0.27 | −0.06 | 0.949 (0.916) | −0.24 | 0.808 (0.783) | 0.28 | 0.782 (0.811) |
| T | A | 0.24 | 0.22 | 0.26 | 1.18 | 0.240 (0.230) | 1.18 | 0.239 (0.222) | 0.59 | 0.552 (0.566) |
pa—values calculated for haplotype frequencies, comparisons between the control and study group, minimal haplotypes’ frequency taken into account during analyses—5%, p values corrected according to the sex are given in parentheses, score—magnitude and direction of effect, †—global significance test.