Table 8.
Association analysis between MSX1 (rs8670; rs12532) haplotypes and total number of impacted teeth; total number of haplotypes taken into account during analyses: n = 202.
|
MSX1 NM_002448.3:c.[6C > T; 276A > G] |
Frequency | Additive | Dominanat | Recessive | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 6.44; df = 2; p = 0.040 * (0.038 *) † | 9.65; df = 3; p = 0.022 * (0.021 *) † | 1.30; df = 3; p = 0.729 (0.720) † | ||||||||
| rs8670 | rs12532 | General | TNIT ≤ MED |
TNIT > MED |
Score | p | Score | p | Score | p |
| C | G | 0.27 | 0.32 | 0.20 | −2.48 | 0.013 * (0.012 *) | −2.64 | 0.008 * (0.008 *) | −1.11 | 0.266 (0.254) |
| C | A | 0.47 | 0.45 | 0.50 | 1.01 | 0.313 (0.297) | 1.64 | 0.102 (0.100) | −0.05 | 0.957 (0.987) |
| T | A | 0.26 | 0.23 | 0.30 | 1.46 | 0.144 (0.147) | 1.77 | 0.076 (0.075) | 0.16 | 0.876 (0.899) |
p—values calculated for haplotype frequencies, comparisons between the subgroup of patients with a total number of impacted teeth below the median value (TNIT ≤ MED) and the subgroup of patients with a total number of impacted teeth above the median value (TNIT > MED), minimal haplotypes’ frequency taken into account during analyses—5%, values corrected according to the sex are given in parentheses, score—magnitude and direction of effect, †—global significance test, * statistical significant difference p < 0.05.