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. 2021 Apr 19;18(8):4324. doi: 10.3390/ijerph18084324

Table 4.

Synergistic effect between BMI and smoking status on the risk of gout (N = 385).

Characteristics Healthy Control Group
(n = 304) (%)
Gout Group
(n = 81) (%)
OR (95% CI) AOR (95% CI)
BMI ≤24.9 kg/m2 and non-smoker 106 (34.90%) 6 (7.40%) 1.00 1.00
BMI ≤24.9 kg/m2 and smoker (active smoker and exposed to SHS) 45 (14.80%) 16 (19.80%) 6.28 (2.31~17.09) ** 3.18 (1.01~9.97) *
BMI >24.9 kg/m2 and non-smoker 106 (34.90%) 16 (19.80%) 2.67 (1.01~7.08) * 1.94 (0.66~5.64)
BMI >24.9 kg/m2 and smoker (active smoker and exposed to SHS) 47 (15.40%) 43 (53.10%) 16.16 (6.43~40.58) ** 9.65 (3.25~28.65) **

Note: BMI: Body Mass Index; OR: odds ratio; AOR: adjusted odds ratio; CI: confidence interval; SHS: second-hand smoke. OR was calculated with a binary logistic regression test. AOR was calculated with a multiple logistic regression test adjusted for alcohol consumption, gender, educational level, age, urate levels, systolic blood pressure, and body-mass index. * Indicates a significant difference in values between groups at p < 0.05; ** Indicates a significant difference in values between groups at p < 0.01.