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. 2021 Apr 19;14(4):380. doi: 10.3390/ph14040380

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Photomicrographs of CA3 area of rat hippocampus proper: In control rats (G1), pyramidal cells showed heavily studded cytoplasm with Nissl granules (arrows). In (G2) (PILO rats) and (G3) (PILO+LPS rats), marked decrease in Nissl granules content was observed in pyramidal cells (arrows). On the other hand, Nissl granules were increased (arrows) mildly in (G4) (PILO+LPS+VPA rats), moderately in (G5) (PILO+LPS+Celecoxib rats) and markedly in (G6) (PILO+LPS+VPA+Celecoxib rats). Stain, toluidine blue. Bar 50 µm.