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. 2021 Apr 18;22(8):4198. doi: 10.3390/ijms22084198

Figure 1.

Figure 1

Body weight and serum parameters. (A) Body weight and (B) serum glucose levels were measured at baseline and monthly thereafter during the experiment (n = 10–12 animals/group). At the end of the experiment, serum samples were collected. (C) Serum TG levels were measured using an enzymatic colorimetric assay kit (n = 10–12 animals/group). (D) Serum concentrations of leptin, (E) TNFα, and (F) resistin were quantified using a MILLIPLEX® Mouse Adipokine Multiplex Immunoassay (n = 10 animals/group). Values are presented as mean ± SEM; ○ indicates wild-type male group vs. wild-type female group; Δ indicates APOB-100 male group vs. APOB-100 female group; + indicates APOB-100 male group vs. wild type male group; # indicates APOB-100 female group vs. wild type female group; * denotes p < 0.05; ** denotes p < 0.01; *** denotes p < 0.001. WT/ND, wild-type mice on normal diet; APOB/HFD, APOB-100 transgenic mice on high-fat diet; TG, triglyceride.