Heatmap of relative gene expression differences in adipose tissues and in the liver in response to hyperlipidemia. The relative expressions of different endocrine and cytokine factors, receptors, and transport proteins were studied in adipose tissues and in the liver of healthy and hyperlipidemic mice using qPCR (n = 6 animals/group). For APOB/HFD vs. WT/ND comparisons, the relative expression of target genes in transgenic animals was compared to the expression levels detected in wild-type animals (results are given as a percentage, where WT/ND groups = 100%). For the female vs. male comparison, the relative expression of target genes in females was compared to the expression levels detected in males (results are given in percentages, where the male groups = 100%). WT/ND, wild-type mice on normal diet; APOB/HFD, APOB-100 transgenic mice on high-fat diet; BAT, brown adipose tissue; WAT SC, subcutaneous white adipose tissue; WAT VIS, visceral white adipose tissue.