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. 2021 Apr 20;13(4):290. doi: 10.3390/toxins13040290

Table 2.

Short Linear Motifs (SLiM) conserved in exposed regions of snake venom Group II.

Motif
Description
ELM Class Sequence Section
Start–End
Fraction of Proteins Containing the Motif in the Specified Section
Myotoxins Neuro-Myotoxins Neurotoxins PLA2G2A
NOT D49 D49 NOT D49 D49 D49
Pin1 site, and
PDK and CDK phosph. sites
DOC_WW_Pin1_4
MOD_ProDKin_1
MOD_CDK_SPK_2
35–37 0/25 0/14 1/5 1/9 4/12 10/10
SH2 binding site LIG_SH2_CRK 51–55 23/25 9/14 3/5 6/9 9/12 0/10
PKA phosph. site MOD_PKA_1 52–56 23/25 3/14 3/5 1/9 0/12 0/10
FHA binding site LIG_FHA_1 59–65 0/25 0/14 0/5 2/9 4/12 10/10
Pin1 site and
CDK phosph. site
DOC_WW_Pin1_4
MOD_CDK_SPK_2
119–121 0/25 0/14 0/5 0/9 0/12 7/10
PDZ binding site LIG_PDZ_Class_3 119–121 23/25 9/14 5/5 5/9 10/12 0/10